CBD Effects on Kidneys : With CBD’s recent popularity peaking, adverts for the compound have appeared everywhere on the internet, billboards, and TV, and even social media.

Presently, kidney disease is the ninth most common cause of death in the United States, and the situation is not improving. A common symptom is physical and emotional pain, that may vary in intensity depending on the patient.

In general, doctors prescribe painkillers as a treatment for the pain, but they are usually excreted by the kidneys, which can cause more kidney damage. How could CBD prevent further kidney damage?

CBD Effects on Kidneys

Studies suggest that CBD can relieve pain. Early trials of CBD suggest that it may benefit the kidneys as well due to its potential anti-inflammatory, pain management, blood pressure stabilizing, and anxiolytic effects. Let’s delve into the effects of CBD on the kidneys.

What Is CBD and Its Potential Effects on the Kidneys?

In contrast with Tetrahydrocannabinol (THC), Cannabidiol (CBD) is non-psychoactive, and so it will not make you high. This compound is also a viable option for treating aches, symptoms of anxiety, and inflammation.

CBD may have an advantage over other pain medications like acetaminophen in that the latter is metabolized by the liver and eliminated by the kidneys.

In addition, they might damage the kidneys, causing worsening of the condition. CBD, on the other hand, is also metabolized by the liver, but does not appear to cause any damage as it is not toxic.

Some of the potential effects of CBD on the kidneys are as follows: 

  • Could help to reduce kidney inflammation
  • The pain associated with kidney ailments may be alleviated by this medication
  • A drug that slows the progression of kidney disease
  • Possibly prevents oxidative damage in the kidneys.

What Is Kidney Disease?

Its main role is to clean blood and remove excess fluids in the body. The fluids are discarded from the body as urine. The kidneys are an important part of the body and once impaired by diseases, may have serious implications.

It is generally possible to survive for many years without one kidney, so kidney donors and recipients survive for many years. However, if both of your kidneys fail, then you would be in a fatal condition and would need a kidney replacement in order to survive.

Acute kidney disease can also evolve into chronic kidney disease under severe circumstances. Here are the different types of kidney disease:

Chronic Kidney Disease

People with chronic kidney disease are generally unaware that they have it, which can be quite overwhelming. Unfortunately, chronic kidney disease does not get better with time but only worsens.

Waste builds up in the body since the kidneys are not working well. In advanced stages, the kidneys may fail completely, becoming life-threatening. When this happens, you may need dialysis to remove the excess fluids.


The glomeruli are the tiny blood vessels that allow the kidneys to purify themselves. An infection or congenital condition can therefore cause the glomeruli to become inflamed. The majority of glomerulonephritis cases resolve themselves with time.

Kidney Stones

A good example of this is mineral particles. Over time, these minerals crystallize, creating kidney stones. Everyone is able to pass them out naturally, but the process can be painful sometimes. You may need surgery to remove them in severe cases.

CBD and Kidney Disease


You will have fever above 102°F, cloudy urine, painful urination, pus in the urine, and nausea and vomiting. This condition can be treated with antibiotics, and in severe cases, you may need to be hospitalized.

A polycystic kidney disease is a disease of the kidneys

It is common for the kidney to form cysts or fluid sacs on its surface. Most of them are usually benign and have no severe side effects. Polycystic kidney disease is a genetic condition that will cause the kidneys to grow numerous cysts all over the surface. It can even lead to kidney failure if the cysts interfere with the regular functioning of the kidneys. However, if both of your kidneys fail due to polycystic disease, you might need dialysis.

The Effects of Kidney Disease

Below are some of the effects seen in result to kidney disease:

  • Lowered immune function
  • Bleeding disorders
  • Anemia
  • Heart failure
  • High blood pressure
  • Skin disorders
  • Hypercalcemia
  • Neurological disorders
  • Acidosis
  • Hyperkalemia

Kidney diseases: sources and causes

Each day, around 180 liters of blood get filtered by the kidneys. Diabetes is one of the most common causes of kidney disease. Diabetes leads to high blood sugar levels, which damage tissues, including the kidneys.

Hypertension is the second most common cause of kidney disease. Hypertension reduces the blood supply and the autoregulatory response of the kidneys, which causes nephrons to get damaged and put a strain on the remaining nephrons. The other causes include:

  • Heart disease
  • Obesity
  • Lupus
  • Smoking
  • Hepatitis B and C

CBD and Kidney Disease: Where Does It Fit?

The effects of CBD may provide relief from kidney diseases, but does CBD boost production of natural cannabinoids or inhibit the mechanisms of these receptors?

The use of CBD might also promote renal function because it might protect the kidneys from inflammatory and oxidative damage, as well as the nephrons as a whole.

According to the type of renal injury, CBD may also help to maintain normal functioning of the glomerulus. It can also reduce problems with the body’s filtration mechanisms.

Pain Management

This has been done by blocking FAAH, a fatty acid needed to break down anandamide and keep more in the body. CBD is an analgesic, and has been shown to help relieve pain in arthritis and other conditions.

Anandamide acts on the CB1 receptors in the body to control your pain response. Kidney disease can be a grueling experience with inflammation of the organ, incisional pain from surgery, stone and kidney disease, and even dialysis.

Inflammation Reduction

It has been studied that CBD may have anti-inflammatory properties, and since most kidney diseases are inflammatory, it may have a positive impact on the inflammatory symptoms. This is because CBD stimulates the endocannabinoid system.

Reduces Nephrotoxicity

Various toxins affecting the renal function of the kidney phrotoxicity.d to as Nephrotoxicity. CBD might help reduce the toxicity of drugs by working with the cannabinoid receptors in the kidney. This can contribute to better kidney health.

Diabetes Prevention

Studies have shown CBD may be able to reduce inflammation in diabetes. Diabetes is a risk factor of kidney disease. CBD may be able to help.

What Is the Recommended Dosage of CBD?

When it comes to CBD, you should always talk to your doctor, especially if you have any health conditions or are taking medications. CBD can interact with certain medications, so it is always best to speak with your doctor before you start CBD.

The right dose of CBD may be difficult to find, as it affects each person differently. Therefore, you should follow the manufacturer’s instructions and start low and slow. Note how your body responds and adjust accordingly as needed.

Final Words

A severe form of kidney disease can be fatal. Additional research is needed in order to fully comprehend the effects of CBD on kidney function. However, CBD does appear to have several potential benefits. Always consult with your doctor before taking CBD.

A trusted and transparent source will provide third-party lab tests, along with a certificate of analysis, when looking for the right CBD product for you.


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